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Tissular pathology D. General pathology E. Pathology by systems F. Pathology by regions G. Tumoral pathology H. Case records K. Info - Admin Resources in pathology Technical section. Function The lysosomes are used for the digestion of macromolecules from phagocytosis ingestion of other dying cells or larger extracellular material , endocytosis where receptor proteins are recycled from the cell surface , and autophagy where old or unneeded organelles or proteins, or microbes which have invaded the cytoplasm are delivered to the lysosome.
Fusion Live-cell imaging has shown that fusion with lysosomes occurs by both transient and full fusion events, and yeast genetics and mammalian cell-free systems have identified much of the protein machinery that coordinates these fusion events.
In addition to their role as the digestive component and organelle-recycling facility of animal cells, lysosomes are considered to be parts of the endomembrane system. Lysosomes also use their hydrolytic enzymes to destroy pathogens disease-causing organisms that might enter the cell.
In a process known as phagocytosis or endocytosis, a section of the plasma membrane of the macrophage invaginates folds in and engulfs a pathogen. The invaginated section, with the pathogen inside, then pinches itself off from the plasma membrane and becomes a vesicle. The vesicle fuses with a lysosome. A lysosome is a membrane-bound cell organelle that contains digestive enzymes.
Lysosomes are involved with various cell processes. They break down excess or worn-out cell parts. They may be used to destroy invading viruses and bacteria. If the cell is damaged beyond repair, lysosomes can help it to self-destruct in a process called programmed cell death, or apoptosis.
Now, the lysosome is a specific type of organelle that's very acidic. So that means that it has to be protected from the rest of the inside of the cell.
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